Retinoic acid pathway genes show significantly altered expression in uterine fibroids when compared with normal myometrium
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چکیده
منابع مشابه
Retinoic acid pathway genes show significantly altered expression in uterine fibroids when compared with normal myometrium.
Fibroids are benign neoplasms of myometrial smooth muscle cells (SMC). Despite being the most common tumor in humans, their etiology is poorly understood. Recent microarray studies have demonstrated that multiple members of the retinoid pathway are differentially expressed between myometrium and fibroids. The aim of this present study was to investigate gene expression of members of the retinoi...
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The aetiology of uterine fibroids remains unknown, despite causing significant gynaecological morbidity. Fibroids have a reduced microvascular density when compared with adjacent myometrial tissue. The aim of this study was to identify genes with differential expression between fibroid and adjacent normal myometrium, particularly genes with a role in angiogenesis. Total RNA was extracted from f...
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Thioredoxin is a small multifunctional protein which acts as a dithiol hydrogen donor for ribonucleotide reductase in DNA synthesis. Thioredoxin participates in the regulation of different metabolic processes, such as changes in the activity of different enzymes, receptors or transcription factors. The aim of the present study was to determine possible differences in the expression of thioredox...
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ژورنال
عنوان ژورنال: MHR: Basic science of reproductive medicine
سال: 2007
ISSN: 1360-9947,1460-2407
DOI: 10.1093/molehr/gam040